From Microsoft:
To uninstall the SkyDrive
If you uninstall the SkyDrive desktop app from your PC, your SkyDrive folder will stop syncing. The SkyDrive folder and your files on SkyDrive.com won't be deleted.
In Windows 8, follow these steps:
Swipe in from the right edge of the screen, then tap Search.
(If you're using a mouse, point to the top-right corner of the screen, move the mouse pointer down, then click Search.)
Enter SkyDrive , and then tap or click Apps.
In the search results, swipe down on the SkyDrive icon that has a folder, and then tap Uninstall. (If you're using a mouse, right-click the SkyDrive icon that has a folder, and then click Uninstall.)
In Windows 7 or Windows Vista, follow these steps:
Click the Start button Start button. In the search box, type Programs, and then, in the list of results, click Programs and Features.
Click Microsoft SkyDrive , and then click Uninstall. If you're prompted for an administrator password or confirmation, type the password or provide confirmation.