because you fly something with xfer pumps i feel deeply unqualified to comment....
but i will say some time ago i flew a 172S which for some odd reason wasn't taking fuel from both tanks evenly (it had the G1000 suite so i had visual and audible warnings) it was giving a low fuel indication on left tank but 3/4 full on the other, instead of taking BOTH on the return leg take off i went for FULLEST didn't fancy a cough from the engine climbing out with 4 pax on board...
Just me.. switched back to BOTH and monitored all the way home...