Walkerjoe,
I've flown the L-1011, B747-400, -400F, 757ER, 767-200/300ER, and the 777 (currently). Go ahead and e-mail me with specific questions if you like, and I'll endevour to get them answered, or I'll have a think during my next trip and post here. My longest flight is 15.45 hours in a -400, LAX-HKG.
Personal body-clock time is the single biggest factor controlling fatigue, IMHO, but it's interesting to see how the designers tried to mitigate its effects.
Cheers