CRJ just isn't a profitable machine to operate. Take for example a 37,000kg CRJ 700 burning 1.5t /hr and a widebody at say 233,000kgs burning 6t hr means:>
233/6 =38.83 tonnes of aircraft lifted per hour per tonne of fuel burnt as opposed to 37/1.5 , therefore you are burning 50% more fuel for less weight carried. And of course that is to say that the CRJ 700 is operating at max weight (ie best loads?).
Thats simple economics before you talk about routes / loads etc etc.
C Ya.