From personal experience if you were considering taking off extremely heavy then I would give serious thought to loading up the nose locker with a substantial amount of weight. Ignore the 45kg limit placarded and fill it with weighty things (not sure what you might be able to find) untill it won't take any more.
The six will take a great load but try and keep the weight well forward. Also, find a nice long runway to leave from.
Good Luck.