Many years ago a woman with Thalidomide disablement was flying a K13 fitted with an unauthorised hand wheel rudder which required an instructor with a pair of snips to cut the wires if required so as to render the a/c "serviceable". He remarked " I'll get the brakes if you like". Her reply "Who's flying this bloody thing, me or you?" & continued to make a perfect landing. There was some debate about whether she could go solo but regulations were all that got in the way.
Another was a guy with Cerebral Palsy. He worked for some kind of Artificial intelligence unit at Edinburgh, couldn't stand up un-aided, couldn't speak legibly but we discovered he was left handed & could fly very well once he had a grip of the stick. I have every respect for such people.