I can't comment on the 767 as I've not flown one.
On the Douglas/Boeing 717 there is no inflight realignment possible.
And as to BOAC's question about grubby hands being there, the reinforced cockpit door open/deny knobs on out entire fleet, are located on the adjacent panel to the IRS. The three IRS knobs and the door knob are of similar size and shape, and to open the door, one turns the knob in the same direction as turning the IRS off.
I'm aware of a couple of instances where pilots have gone to open the door but sadly grabbed the wrong knob, and only found out when the autopilot tripped off half the screens went blank, and the door unlock siren failed to sound.
