Not a chance that Vueling would operate MAD-BHX any time soon !
Vueling bases are Barcelona/Toulouse/Amsterdam/Paris and soon Florence.
Madrid only has a very few holiday routes and connections to other bases (Paris/Barcelona/Florence).
The only carrier likely to fly BHX-MAD would be Ryanair.
Outside chance for Iberia Express but only if IAG reconsider the UK regions.
Air Nostrum from Glasgow and Manchester didn't last long.