No problem...
Mailwasher has the ability to recognise spam using matches against email address (user-configurable too). Also it links in with spam relays. Tehran? Haven't had it delete wanted mail yet. You could always set the mailer up in the "buddy" list.
When you've identified the spam, it'll add them to the blacklist for furter reference. The good bit is that you can send a bounce message back to the sender in some cases. Spammer sees this and then deletes you from their list. This feature has cut my spam volume down. Wish it could pattern-match on content too...
Remember to pay the programmer if you like it!
P.S. We have a .aero domain here at work. There hasn't been a problem with receiving spam as a result of our registration.