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Old 25th Nov 2012, 15:28
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It's to prevent unpleasant fumes from de-icing fluid entering the cabin via the APU.

Quote from the 737 AFM:

Note: If Bleeds OFF take-off performance is required after de-icing, perform the ‘Unpressurized’ Take-off procedure, and ensure APU BLEED air switch is OFF.
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