A PPL with MSFS experience, maybe not, but two mythbusters with absolutely no experience did it when they had help on the radio...
Myth: Person With No Flying Experience Can Land : Discovery Channel
They each tried twice, on the first try they had no outside help and each of them crashed the simulator. On the second try, with someone talking them through the process over the radio they each were able to land the plane safely, and they were manually flying the plane.
two for two, no help, crash
two for two, with help, land safely
does this prove anyone can do it? no, does it prove it can be done? I think yes.