Knobby - some more things I remember from the trip...
Not much at Everglades City itself, but right next door is a place where you can get everglades boat rides which are worth taking if you have the time.
We originally planned to stop at Homestead, but changed our minds enroute and carried straight down to EYW. Total time from Naples was about 2h30m.
We went to Venice from Naples with the intention of going to Sharkeys, but there was a very long queue, so we had to give it a miss. Anyone else been there lately?
I think there is only one FBO at EYW - they are OK and will arrange fuel, taxis etc, but probably due to the number of visitors they are not the most friendly place we visited in Florida. You will need to pay a parking fee (no problem for us UK pilots who are used to it). The taxi into town is also quite expensive by US standards (about $7 per person if I remember correctly), again no problem for us London folk.
We flew to Marathon from Key West (and back again the same day). A great flight for a summers day. There are a couple of FBOs at Marathon, but not much else on the airfield. We took a taxi from there to the Dolphin Research Center, where you can swim with dolphins as long as you book well in advance (checkout their website). The FBO at Marathon arranged the cab for us.
Have fun!