This is such a no-brainer that I am surprised rational people even bother to discuss it.
Who is going to pay for the certification process? It will take years and vast bucketloads of money.
No airline would put money down until it was tried, tested and accepted by every national authority in whose airspace they might want to fly the aircraft.
What incentive is there for the country I live in to accept pilotless airliners flying over its cities and into its airports?
But let’s assume that the financing and the politics are somehow magicked out of the equation.
Suppose you are the first to order a fleet of such aircraft. How will you sell them to the public? ‘Fly pilotless because …’
Suppose you are a competitor, still using pilots. What will be your selling pitch? ‘Fly with a highly trained professional because …’
Suppose you are a passenger faced with the choice between these two.
It just ain’t gonna happen.