IMHO
1. What do you want to do?
2. All equal, hopefully no negative change, what is the lifetime earning potential, to include provident funds or pension?
3. What is the job security and the stability of the companies?
4. What is the quality of life and benefits?
5. Would you truly be happy overseas? What about your family?
Those are some of the questions you should consider. Here in the States many hold command on RJ's or some other reasonably well paying National Airline, but when time comes, nothing beats being at the majors. Most will actually take a pretty good pay cut and move to the right seat, but on the long run, it's worth it. Of course, now many wish stay stayed at their previus job, but no one could predict Sep 11 and the following rapid decline of aviation.
Good luck with your decision.
What are your qualifications?