rennaps:
I wouldn't like to fly an RNP 0.1 AR approach procedure by hand.
You would just have to cough to be outside the protection area.
Also can one fly an RF leg by hand?
In the U.S. at least most operators permit an RNP AR 0.30 IAP to be hand-flown but using the flight director. Below 0.30, autoflight is required.
Presumably, a departure with an RF leg should be not less than RNP 1.0, which would be quite easy to hand fly with the flight director.