The eTrex just arrived this morning, excellent delivery time from the suppier! So far have only used it to navigate around the back garden, so about 100ft total distance!! Am impressed by the display and simplicity and can't wait to take it in the aeroplane...
Haven't used the 12, so can't comment, although I don't think it has a trip computer like the eTrex. Good Luck choosing!!
Oh, PS: The eTrex is most definitely one hand operation, and for size indication it's about 2/3 as long and twice as thick as my Nokia 6210.