Just say "unfamiliar" and they'll give you vectors, or a published VRP, or whatever
Will they give you a description of it to start with? I remember going to Liverpool once and being asked to route via Seaforth - not having a clue what I was looking for, I used the GPS to get me there but i was cleared along the river anyway before I got to it, so didn't really take any notice of it. I looked it up when I got back.
There are loads of VRPs which are unclear from the name, a roundabout, town centre, cement works, dock etc. etc.