Some valid points here about both the 'meeting imperative' getting in the way of appropriate aviation safety related issues and the lack of focus on aviation issues when thinking about business issues.
Personally I have achieved this quite a bit although I have often made an early decision to go by public transport only to find the weather conditions expected where more benign than forecast and I have missed th opportunity for a pleasant trip part paid by the business.
Living in Norfolk and having business interests across the UK flying is a sensible option and public transport is not always cheaper or quicker.
Recently had to do Norwich to Folkestone, a journey I had done (via Lydd) with ease previously. By train it was no cheaper and took nine hours of travelling time.
Similarly board meetings in Cheltenham and Preston seem to cry out for travel by Formationfoto-air.
One precaution I do take is to share the flying with a friend as often as possible. He flies there (whilst I am thinking about the business meeting) and I fly back. This removes many of the downsides and he gets some free flying.
Have managed to fly Seething to Audley End a few times in the Jodel to visit the PILOT offices. Not really justifiable in commercial terms but it hels to arrive fresh and to llok down on others making the same journey by car along the A14.