You could use your FMC to find out. Make sure all your enroute winds are on the RTE DATA page. Have one MCDU with the fuel remaining at destination showing. Use the other MCDU to change the Cost Index ...without executing (give it time, it takes a few seconds to calculate)... until you find the CI with the highest fuel remaining at destination. Then Execute that CI. Do NOT use LRC. It isn't wind compensated.