Typical inflight fuel restriction for most aircraft bigger than puddle jumpers.
Usual reason is for wing bending relief. That is to say, the fuel in the outboard wings tends to reduce the extent of wing bending in the vertical (pitching) plane for a given flight load compared to having more of the fuel inboard (or in fuselage/centre section) tanks.
Unless there is a specific refuel limitation, it is not significant how the actual refuel is performed.