It is quite simple really, the only chance you have is with the autopilot and autothrottle engaged, listen to what your told and hope for goodness sake you don't press the wrong switch.
I fly a 737 classic, it has 500 switches in there, any takers!
If I were a passenger on a flight faced with this situation, I would hope that someone on the ground would be able to help me tune the nav boxes, set the aircraft up etc for a autos land. The simple thought of manual flying is not open to question, you would be too overloaded to deal with everything.