Sure you won't be able to land back (unless there is an ILS) but that is a risk no different to other risks in aircraft operation.
If you are expecting a fire in the cockpit at any moment after departure, then I would agree that being able to land back at the airport of departure is fairly important...
The higher altitude wx (icing conditions, etc) is obviously most relevant to whether one should go or not, but one doesn't need a 200ft overcast scenario for that to be relevant.