Im at QR flying the Airbus, funnily enough where a lot of the VA guys ended up after they dropped kicked them out the last time. I did 870 hours last year, and I can honestly say I have never felt so tired in all my flying career.
To be honest, not sure if it is industry standard as I haven't flown long-haul before, but my next move will be back to short haul and i'll stay there, I can't imagine doing this type of flying AND having a young family + a Mrs that works.
I suppose if its 500-600 hours a year it might be bearable, but personally if you actually like 'flying' the aeroplane LH is damn boring!