The most significant divert I had, entailed a completely different route to the one expected. I was doing a project in HKG in the mid 90s and used VS. At the time, the usual route home was South: Thailand/India/Gulf/Med but on my return run at the end of the project, we were told (just before Push) that there was such a big storm to the South that we would go North, almost as far as Bejing before turning West. It added a full hour to the trip but it was a smooth ride.