Shall I hazard a prediction?
At some point, a 330 min ETOPS (or even 220) will go in with loss of all persons. ETOPS will get restricted during the investigation. Depending on the outcome, it might even be restricted a bit longer.
But, ETOPS (or any other acronym) is the only game in the world and it WILL continue. Inevitably, this being a human enterprise, some people will die.