Hi NNC, here’s the experience:
My colleague had just finished his “V1”-callout as the nose violently started pitching up. We were instantly airborne with about 25° pitch, increasing. Pushing the yoke almost to its forward limit plus simultaneously starting trimming was just enough to regain adequate control...!!!
This happened on a 737-300, when 400kgs of cargo were loaded into the aft hold, but, on the loadsheet, trimmed in the forward hold (and this, btw, is NOT a sim-experience)! Recalculation revealed that we were only barely out ot limits!
You might also consider that on top of pure control-problems due to out of CG-limits, you also may have the aggravating effects of a wrong stab-trim setting.
@john_tullamarine:
And, yes, heads were rolling at this outstation and procedures were adopted!