PPRuNe Forums - View Single Post - 37 year old ex-soldier (please sign) petition Cancer treatment
Old 23rd Nov 2011, 18:38
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airborne_artist
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He's not been able to access Avastin because someone (probably a committee/group in fact) has decided it's not suitable/cost-effective for him given the condition he is in.

I don't know his circumstances, but they have decided he's not likely to benefit sufficiently from the drug as much as others will benefit from other drugs costing the same.

I've had a small insight into the way these decisions are made and while it looks brutal it's the only way when there is a finite amount of cash.

A quick Google reveals:

"The U.S. Food and Drug Administration approved the use of Avastin last month for the treatment of brain cancer. The powerful drug shrinks tumors by choking off their blood supply. However, about fifty percent of patients don’t respond to the therapy, exposing them to unnecessary side effects and medication costing up to $10,000 per month." (Avastin for Brain Tumors | MedNews)

"Therapy for treating recurrent high-grade gliomas is palliative. All patients with these high-grade tumors eventually die of their cancer.

While treatment with Avastin does dramatically improve survival time, the time that patients have left is of better quality and less about living with the disease itself," Chamberlain said. In this study, the patients, ages 24-60, received an infusion of bevacizumab every two weeks for an average of 14.5 cycles (range was two to 39 cycles). Fourteen (64 percent) patients showed a partial response to the medicine as shown on radiographic scans. Two patients had stable disease and six had progressive disease. Progression-free survival ranged from three to 18 months and survival for the entire group of patients was three to 19 months" (Avastin Effective At Delaying Brain Tumor Progression In Recurrent Disease)

Opinions on drug impact will always vary. It's not an exact science.

There is no cure for his condition.
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