Stats tell us very little in these cases. Most of the reports I have read recently, involve twins ditching, not SEP. Most recent crashes I have read, recently, on land, involve twins. So what?
Until the facts are known in this incident, then talk of SEP vs Twin over water (done previously), twins vs SEP over cloud (done previously) is frankly futile.
This again would appear a culmination of smallish incidents which ended up with the pilot sadly losing his life. Again, at present, actual facts appear scarce, therefore, the report will again be sobering reading. They always are.
Anyway, flying SE, or NE for that matter, would have brought them to land. The outcome may not have been different though.