Total cost of ownership will overwhelm the slight differences is speed and fuel flow
to rephrase the question, putting aside cost of ownership, is it possible to directly compare the FF and range with comparable loads at a fixed altitude? Assume 2 adults, 2 children and some baggage.
We had almost completely decided against the various options because :
Mooney - due simple gear and our requirement for landing on grass (mostly smooth grass).
Bonanza - due range but with tip tanks, looks like it could now fit the bill?
TB20 - due range with load.
DA42 - due question over engine reliability, TBO etc.
SR22 has almost everything that we want but again, may come up short on range.