DozyWannabe:
Unfortunately the DC-10 cabin became very noisy when the rear cargo door blew out and took the floor with it - *briefly* very noisy in one tragic case. 346 dead because of a known design flaw and a "gentlemen's agreement" (none may dare call it a bribe) to prevent a legally-enforceable fix to that design flaw is something for which MD should never be forgiven.
AAL almost lost one over Detroit for the same reason.
Then, there is the UAL DC-10 that landed upsite down killing over 100 folks. It would have been a total wipe-out except for a captain willing to listen to a very sharp deadheading pilot.