Certainly where I fly the runway is long enough, and the usual aircraft types have a steep enough climb angle, that anyone joining overhead, crosswind or through initials* runs the risk of coming into conflict with departing traffic as they cross the upwind end of the runway. Visibility is good, so you always know about them, but I've had some hairy moments.
Tim
*a military perversion you only need to know about if flying at a military field, though I think it's in CAP413.