While I'm sure there at least some similarities that you see, it's the ones that you don't consider that torpedo your argument below the proverbial waterline..
1. You're not operating across multiple time zones, all the more exacerbated if you're going west to east, against the clock. The adverse effects on your circadian rythm are proportionally smaller given your slower than jet speeds and crossing fewer time zones within a given timeframe.
2. You're not carrying passengers, but inaminate freight, and transporting the former involves a higher legal standard of care. Of course, if you're driving hazmat loads, or ones that could make a very loud "boom", you could kill as many on the ground as might be seen with a passenger aircraft accident.
3. You're operating in a 2 dimensional world, and not a 3 dimensional world. If you nod off and run off the road and come to a safe stop somewhere (assuming you don't run into something/someone in the process), you're still alive to drive another day--not so if you're flying a planeload of pax.
The common-sense bottomline here, irrespective of flying any aircraft, or driving any type of vehicle, is not to operate one when you're tired, or impaired. Period.