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Old 5th Aug 2011, 22:14
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FlyingGoat
 
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I have not had the PSA test because it is ~ 75% false positive and then your only option is to have the biopsy whose mortality is comparable to the risk of a man in his 50s having prostate cancer and dying of it.

There's a lot of misunderstanding about the PSA test - for a start, the results aren't a straight positive or negative. What's more informative is the trend over time, and rate of change, if any. Prostate size is related to PSA - another neglected aspect. There are also alternatives to biopsy, including PCA3 and MRI. Mortality and morbidity from biopsy is negligible (see ERSPC 2010).

What's more interesting is reliable research which shows that approx. 40% of men in their 40's, 50% in their 50's, 60% in their 60's etc. have at least the initial stages of prostate cancer - you won't find many GPs who are aware of those stats, and it's not an argument for screening - most will die of other disease or natural causes.

More info on PCA3 here and on combined MRI/Biopsy here.

Caution with the above - I have no medical qualifications.

Last edited by FlyingGoat; 6th Aug 2011 at 08:00.
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