The saddest realisation to me, on the limited info available, is that if this crew had resisted the urge to act, and just sat and watched, they may well all be alive today.
The hardest thing for any modern pilot today, is to NOT react to a screen full of warnings, and aural callouts, but to watch and fully assimilate the information available.
The 'hand-fly heros' may not have won this game either...