I expcted to bin my Agfa scanner when I moved on to XP but newer drivers kept it up and running. Didn't work with Win7 though and I was searching for recommendations for a new one when I came across a reference to Vuescan.
That reminded me that I had bought a copy ages ago to run my slide scanner using ME so I found the installation disks and, to my amazement, it worked without any problems and my ancient scanner is running again!
The program is expensive but well worth a look.