US Navy seems to think it can be done with mouse clicks, if you believe Fox News (yes I know - never believe the gutter press...
The Navy's X-47B Will Be So Autonomous, You Can Steer It With Mouse Clicks - FoxNews.com
'Speaking to reporters at the Sea Air Space convention near Washington, reps from both Northrop Grumman (maker of the X-47B) and the Navy said the X-47B would be piloted not by human handlers in some steel box in Nevada, but by 3.4 million lines of software code. The rest of its functions will be able to be handled by non-pilot personnel (or your average child), as they will only require clicks of the mouse; a click to turn on the engines, a click to taxi, a click to initiate takeoff, etc.'