This week, I was on a VS A346 CPT~LHR, which is 12 hours. Seated in 21A, a PE seat just at the leading edge of the wing.
Overall, it was very comfortable. Interestingly, I could see the slight rolling motion but could not feel it. The roll was small but continued for much of the flight and was seen by the wing against distant clouds.
Noise was, naturally, louder at this point as the #2 was right outside. I also found that my Philips Noise Cancelling headphones were not as effective against the background noise - as they had been on the outbound, which was a 744.