Now that's interesting as although one manual discusses non standard ULD's loaded off-centre and a lateral imbalance effect in the lower holds, another Boeing manual only discusses CLIM in relation to the actual Taxi Weight of the aircraft in relation to the total weight of the lower holds and the restrictions in relation to the Take-off %MAC.
Confusing? Especially when you move on to cargo versions where the main deck cargo lateral imbalance is not even taken into account!