It's called depleted uranium for a reason..and that is that the radiation it emits is reduced. It has done it's time in a nuclear reactor and it's radioactive days are over. The emission from depleted uranium will usually not penetrate the dead layers of the dermis. However if you make it small enough to be inhaled or ingested, then that's a bad thing..so hitting armoured plate with a shell containing a DU core will vapourise some of the uranium.. and that is not good...More relevently, if you ever find a DU mass balance (and they are pretty rare these days) look for corrosion. If present do NOT attempt mechanical removal, just paint with chromate primer and leave well alone.