I do not have a degree in medicine but can only judge and form opinions by the environmental system that encompass my period on this mortal coil.
The major chase by the AV-MED experts is cardio vascular event or predictions.
I have had several friends and even distant relatives die or become complete vegetable life after a Stroke, without any previous cardio vascular untoward systems.
But does the most learned friend look for previous in that field. NO. its too hard and the costs are prohibitive to have a cranium scan for evidence of minor strokes(TIA?).
I ask, Why do pilots of two, four and even 7 seat aircraft have to be subject to more scrutiny in the medical world that a 69 year old Bus driver who can do 90KMH in NZ with 80 passengers on board amongst the worst drivers in the world and the the poorest roads in the civilized world.?