According to the current owner S6 + Jab 2200 has been done before.
Yep, quite a few around, we looked at a Jab powered S6 before we bought a 582 one. Opened the throttle on the jab and got to Vne in level flight, not a chance of that in the 582!
As Genghis the Engineer says, follow the LAA documentation posted in the engineering section, get an LAA inspector & you should have quite a few around if you have any queries.
batninth