If you are encountering a headwind, it will effect only the actual speed you are moving. For example IAS versus GS.
Mark Meeker if you are going to provide a technical answer, then please make sure that it is correct!
Yes, the wind has a direct impact. You have to work out the route distance, then apply corrections for prevailing winds which then determine the flight time and required fuel. Once you have the fuel, you then can load the payload. You might have to decide if its more beneficial for you to fly non-stop with a restricted payload rather than flying with a full payload.
However this is a lesson that you should have thought about before you purchased the 733F !
As for the rest of you, if you had read more of Spanner748 messages, you would have realized that he isn't a pilot...... but at this stage, I have to ask if he was the right person to be assigned to purchasing an aircraft
Mutt