Continuing along the basics of manual flight:
270 tons flight, all attitudes approximate to about one degree (which is more accurate than I can fly anyway, and that's on a good day

). Rules of thumb in italics.
Rotate slowly (2.5˚ to 3˚ per sec) to just over 10˚ pitch initially (or 10˚ for engine failure scenario), at which point you should hear the click of the landing gear lever latch retracting, announcing you're airborne. At typical thrusts and flaps 20, 12.5˚ will hold V2+10 nicely. For flap 10 it will be closer to 14˚, or more. For 3 engines, pitch at or barely above the 10˚ line should work well.
Acceleration: setting the aircraft pointer box so it is sitting just on the top of the 7.5˚ line works nicely as a place to start: monitor VSI and adjust attitude as necessary to keep 500-1000FPM as you accelerate.
Level flight. At 270 tons and 250 knots, pitching just below 5˚ should keep level flight. Thrust should be about 1.17 (that's an
RB211 epr value, for PW4056/4062 engines at these lower thrust levels, using the RR value and subtracting ten works well, so for 1.17 read 1.07).
Level decel and configuring. Ref30 speed for a 744 is 140 knots at 240 tons.
For each ten tons more or less, add or subtract three knots. Thus Ref30+80 for 270t becomes 140 + (3 x 3) = 149, so Ref30+80 will be just under 230 kts at 270t. You will need just over 5˚, and about 1.16 epr.
Flap 1 will require pitch coming up to just below the 7.5˚ mark, flap 5 will need exactly 7.5˚, and flap 10 somewhere above the 7.5˚ pitch line. Flap 20 is the first setting that will require slightly less pitch, perhaps back down to 7˚. If you are decelerating slowly, 1.1 epr will work nicely, obviously set idle thrust if decelerating more briskly. If you need to maintain prolonged level flight at any of these flap settings, about .01 more thrust is required per flap setting (ie 1.16 at Ref30+80 and clean, 1.17 at Ref30+60 and flap1 etc).
Most flap settings on the -400 don't require that much thought to trimming, except for flaps 20 and 30. Setting flaps 20 she will balloon noticeably, and at 30 she will instead "drop the nose" quite promptly. As a rule of thumb, much like on the classic,
when setting Flap 20 you need 2 seconds trim down to counter, when setting flap 30 you will need 3 seconds trim up.
Setting flaps 20 when the glideslope moves, gear down at one dot below, and flap 30 on the glideslope should work well for a conservative manual approach. For Ref30+5 final approach speed and flap 30, if you always keep the nose pointer box between the horizon line and the 2.5˚ pitch line you should be in the "ballpark". Thus if you see you need more rate of descent, set the pointer box so it just sits on the horizon, if you need less, pitch up so the top of the box sits right under the 2.5˚ pitch line. Thrust will be about 1.18 epr, or 1.23 for three engines (again, that will be about 1.08/1.13 for PW). Obviously these will vary in function of wind component, weight and glideslope angle.
Flare: wait until you hear the "30" RA callout, pitch gently back about two degrees, retard the throttles and hopefully the landing gear lever latch extending and the speedbrake lever whizzing by will be the only indications that you've touched down!