I think you have to be realistic and at times read between the lines when you apply. Sometimes you can see that whoever set the requirements has no clue. Honestly some requirements leave me scratching my head as to how they decided what they require, they certainly aint insurance requirements.
I saw an add the other day, if I can find it I will post it. They wanted pilots for some bizjet, absolute min was 500 hours on type 2000 hours, something like that. They were also looking for a TRE/TRI? That must mean that they have people to train that don't have the minimums they require in the ad. I would say in a case like that it might be worth a shot putting an app in regardless of qualifications.