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It would help to know what route (s) you are lookiung at, but that is for you to say.
Search some airport sites and obtain the following costs:
Parking
Approach and ATC services
Arriving passenger levy
Departing passenger levy
Shared check in facilities levy
Security levy
Are all these waived as the landing fee?
You will also need ground and airside handling. What cost per flight?
De-ice in the winter? it aint cheap mate!
As you have said, other airlines have tried and pulled off with Airbus equipment, but I can think of one TP operator (with SF340s), with economy of scale, by your own posts are not interested.
Is the route designated PSO.
Don't forget the base price of the ticket starts at the APD and works up, add your DOCs and above where applicable, advertising (never under estimate), then additional salaries and costs.
Factor in a buffer for disruption, subbing in the odd aircraft when yours is not available, EU passenger charter compensation...............
Good luck, you may have found a 'niche market' but i doubt it's for long if it works.
Best regards,
Bored