1. It's not an anti fuel-icing additive - it's an anti-water additive. The fuel is quite possibly good to -47ºC but the water that's disolved in it, isn't.
2. It's not particularly nasty stuff. You don't want to be drinking too much of it, and I understand that it should not be used as an eye wash, but you won't die if you do either.
It is carried on 525s routinely - even the 525A. One of the fuel companies did have a standing instruction for a while not to allow it during refueling but I've never been refused.