Knowing the computers and the box is great until !!!! is entered and !!!! is shat out or ATC/WX/terrain/inability/traffic/last nights curry paints a crew in a automation corner.
Yup, EK at MEL was a classic example....as was AA at Cali Colombia, before.
And...before anyone cries 'fatigue' was a factor in the two mentioned, I say...baloney.