As an EASA aircraft they require will require the full medical for the LAPl which some of us can't get.
The NPPL will allow you to fly non-EASA aircraft - ie Annexe II OR Permit aircraft.
At the moment at my airfield there are around a dozen pilots who will not be able to use club aircraft in the brave new world, as they can't get (effectively) a sign-off by an AME. They fly under an NPPL with self-declaration but the LAPL does not allow that post-2012