Do you mean Acronis?
The best way to transfer everything would be to clone the current 80GB disk to the 500. This makes an exact copy of everything on your original disk onto the new one, so all your programs, files and settings are exactly the same.
However, it's a bit trickier with a laptop, because you can't simply connect both disks at the same time to the laptop.
There are a number of ways around this - you could use an external USB disk to hold the image from the original disk, then swap the disks and download it to the 500 (assuming that your cloning software supports external USB devices).
You can do it over the network from the laptop to another PC - but this requires the software to recognise your laptop network card, and you may need an "enterprise" version of the cloning software that supports server-based image distribution.
Or you could get a caddy to allow you to mount at least one 2.5" disk into a desktop PC (either to IDE or SATA connectors) and transfer the image that way - although it would be quicker to put both 2.5" disks into the PC and clone directly.
SD