I have and use a pair of Lightspeed ANR's. They are by far and away the most comfortable headset I've ever tried on. I used to have a pair of David Clarks which were pretty good but the Lightspeeds are miles out front. Have worn them for up to 17 hours (minus 3 quick fuel stops) a couple of times and didn't ever feel the need to take them off.
They get my vote!